MAST's TAP service, including for the IVOA registry, has moved to a new (Python!) platform with a new URL. While we are providing limited forwarding of sync mode queries, updating links in clients provides future proofing, spares network hops, and is less confusing.
https://github.com/astropy/astroquery/blob/main/astroquery/vo_conesearch/validator/__init__.py#L17
https://vao.stsci.edu/regtap/tapservice.aspx/ should be replaced with https://mast.stsci.edu/vo-tap/api/v0.1/registry/, all arguments remain the same.
I can do the one-line PR.