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@pinellolab

Pinello Lab

Massachusetts General Hospital/Harvard Medical School

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  1. STREAM STREAM Public

    STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of single-cell data

    Jupyter Notebook 178 51

  2. CRISPResso2 CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    Python 326 109

  3. haystack_bio haystack_bio Public

    Haystack: Epigenetic Variability and Transcription Factor Motifs Analysis Pipeline

    HTML 47 11

  4. CRISPR-SURF CRISPR-SURF Public

    Python 17 3

  5. PrimeDesign PrimeDesign Public

    Software tool for the flexible design of pegRNAs and ngRNAs for prime editing!

    Python 25 6

  6. MotifRaptor MotifRaptor Public

    Explore the effect of genetic variants on transcription factor binding sites

    Python 8 2

Repositories

Showing 10 of 66 repositories
  • simba-plus Public

    SIMBA+

    pinellolab/simba-plus’s past year of commit activity
    Python 0 1 0 0 Updated Dec 2, 2025
  • ACCESS-ATAC Public
    pinellolab/ACCESS-ATAC’s past year of commit activity
    Python 0 0 0 0 Updated Dec 2, 2025
  • CRISPR-millipede-target Public

    Calculate the enrichment scores of CRISPR alleles and variants from direct target amplicon-sequencing data using Bayesian linear regression model "millipede".

    pinellolab/CRISPR-millipede-target’s past year of commit activity
    Jupyter Notebook 1 AGPL-3.0 0 1 1 Updated Dec 1, 2025
  • cell2net Public

    Mapping multi-scale gene regualtion using single-cell multiome

    pinellolab/cell2net’s past year of commit activity
    Python 0 MIT 0 1 0 Updated Nov 28, 2025
  • pinellolab/CRISPR_Pipeline’s past year of commit activity
    Python 13 MIT 5 6 0 Updated Nov 26, 2025
  • CRISPRme Public

    Variant-aware CRISPR off-target nomination

    pinellolab/CRISPRme’s past year of commit activity
    Python 23 9 1 0 Updated Nov 26, 2025
  • CRISPR-HAWK Public

    Variant- and Haplotype-aware CRISPR guide design toolkit

    pinellolab/CRISPR-HAWK’s past year of commit activity
    Python 1 1 0 0 Updated Nov 26, 2025
  • PerTurbo Public

    Robust and efficient analysis of single-cell perturbation studies

    pinellolab/PerTurbo’s past year of commit activity
    Python 12 MIT 1 1 1 Updated Nov 25, 2025
  • dictys Public

    Context specific and dynamic gene regulatory network reconstruction and analysis

    pinellolab/dictys’s past year of commit activity
    Python 123 AGPL-3.0 15 0 0 Updated Nov 24, 2025
  • DNA-Diffusion Public

    🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

    pinellolab/DNA-Diffusion’s past year of commit activity
    Python 422 54 1 5 Updated Nov 24, 2025

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