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<pclass="w3-large"> The most common central nervous system tumor types can be segmented pre-operatively: <i>glioblastomas</i>, <i>diffuse lower-grade gliomas</i>,
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<i>meningiomas</i>, and <i>metastases</i>. Early post-operative segmentation is limited to the glioblastoma subtype.</p>
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<pclass="w3-large"> All models have been trained using patient data from our partnered hospitals, using the AGU-Net architecture (more details available in the <ahref="#publications">Publications</a> section).</p>
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<pclass="w3-large"> The most common central nervous system tumor types can be segmented pre-/post-operatively: <i>glioblastomas</i>, <i>diffuse lower-grade gliomas</i>,
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<i>meningiomas</i>, and <i>metastases</i>. Common structures are available for segmentation such as enhancing tissue, non-enhancing tumor core, tumor core, FLAIR hyperintensity, and resection cavity</p>
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<pclass="w3-large"> All models have been trained locally using patient data from our partnered hospitals, and using the Attention U-Net architecture (more details available in the <ahref="#publications">Publications</a> section).</p>
<pclass="w3-large">Pre-operatively, the standardized reports include the following tumor characteristics,
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all computed in the MNI reference space: volume, multifocality, laterality, location w.r.t. cortical structures
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<pclass="w3-large">Features computation, the standardized reports include the following tumor characteristics,
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all computed in the MNI reference space: volumes, diameters, multifocality, laterality, location w.r.t. cortical structures
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(MNI, Harvard-Oxford, and Schaefer atlases), and location w.r.t. subcortical structures (BCB atlas).
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The computational pipeline is illustrated to the left.</p>
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<pclass="w3-large">Post-operatively, the rest tumor volume and extent-of-resection are automatically computed.</p>
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<pclass="w3-large">Surgical reporting: brain and tumor volumes pre-/post-operatively are reported, including extent of resection and surgical grading following the RANO2.0 guidelines.</p>
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</div>
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<pclass="fa fa-warning w3-left w3-large" style="color:red;"> Disclaimer: Raidionics has problems running on some specific CPU (cf. <ahref="https://github.com/raidionics/Raidionics/wiki/Frequently-Asked-Questions-(FAQ)">FAQ</a>).</p>
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<pclass="fa fa-warning w3-left w3-large" style="color:red;"> Disclaimer: For macOS users, look carefully to download the correct version (cf. <ahref="https://github.com/raidionics/Raidionics/wiki/Frequently-Asked-Questions-(FAQ)">FAQ</a>).</p>
<p><ahref="https://link.springer.com/article/10.1007/s00701-022-05126-9" class="w3-large"> * <i><b>Pretreatment patient-reported cognitive function in patients with diffuse glioma.</b></i> Schei, S., Solheim, O., Salvesen, Ø., Hjermstad, M. J., Bouget, D., & Sagberg, L. M.. Acta Neurochirurgica, 164(3), 703-711, 2022.</a></p>
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<p><ahref="https://thejns.org/view/journals/j-neurosurg/142/5/article-p1298.xml" class="w3-large"> * <i><b>Prognostic value of manual versus automatic methods for assessing extents of resection and residual tumor volume in glioblastoma</b></i> Majewska, P., Helland, R.H., ..., Bouget, D., & Solheim, O.. Journal of Neurosurgery, 142.5, 1298-1306, 2025.</a></p>
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<p><ahref="https://link.springer.com/chapter/10.1007/978-3-031-72089-5_27" class="w3-large"> * <i><b>Glioblastoma segmentation from early post-operative MRI: Challenges and clinical impact</b></i> Helland, R.H., Bouget, D., ..., Solheim, O., & Reinertsen, I. MICCAI, 2024.</a></p>
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<p><ahref="https://www.sciencedirect.com/science/article/pii/S2772529424000742" class="w3-large"> * <i><b>Incidence, risk factors, and clinical implications of postoperative blood in or near the resection cavity after glioma surgery</b></i> Johnstad, C., Reinertsen, I., ..., Strand, P.S., & Solheim, O.. Brain and Spine, 4, 102818, 2024.</a></p>
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<p><ahref="https://link.springer.com/article/10.1007/s00701-024-06351-0" class="w3-large"> * <i><b>The prognostic importance of glioblastoma size and shape</b></i> Johnstad, C., Reinertsen, I., ..., Jakola, A.S., & Solheim, O.. Acta Neurochirurgica, 166.1, 450, 2024.</a></p>
<p><ahref="https://www.nature.com/articles/s41598-023-45456-x" class="w3-large"> * <i><b>Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks</b></i> Helland, R.H., Ferles, A., ..., Reinertsen, I., & Bouget, D.. Scientific reports, 13.1, 2023.</a></p>
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<p><ahref="https://link.springer.com/article/10.1007/s00701-022-05126-9" class="w3-large"> * <i><b>Pretreatment patient-reported cognitive function in patients with diffuse glioma</b></i> Schei, S., Solheim, O., Salvesen, Ø., Hjermstad, M. J., Bouget, D., & Sagberg, L. M.. Acta Neurochirurgica, 164(3), 703-711, 2022.</a></p>
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