diff --git a/packages/runtime-core/src/renderer.ts b/packages/runtime-core/src/renderer.ts
index f0182c16f64..cccc4ba7efa 100644
--- a/packages/runtime-core/src/renderer.ts
+++ b/packages/runtime-core/src/renderer.ts
@@ -1408,8 +1408,9 @@ function baseCreateRenderer(
         }
         // onVnodeMounted
         if ((vnodeHook = props && props.onVnodeMounted)) {
+          const scopedInitialVNode = initialVNode
           queuePostRenderEffect(() => {
-            invokeVNodeHook(vnodeHook!, parent, initialVNode)
+            invokeVNodeHook(vnodeHook!, parent, scopedInitialVNode)
           }, parentSuspense)
         }
         // activated hook for keep-alive roots.
@@ -1423,6 +1424,9 @@ function baseCreateRenderer(
           queuePostRenderEffect(a, parentSuspense)
         }
         instance.isMounted = true
+
+        // #2458: deference mount-only object parameters to prevent memleaks
+        initialVNode = container = anchor = null as any
       } else {
         // updateComponent
         // This is triggered by mutation of component's own state (next: null)