diff --git a/tfjs-tflite/BUILD.bazel b/tfjs-tflite/BUILD.bazel
index b20a3264c63..a30686ec811 100644
--- a/tfjs-tflite/BUILD.bazel
+++ b/tfjs-tflite/BUILD.bazel
@@ -103,5 +103,6 @@ test_suite(
     name = "tests",
     tests = [
         ":tfjs-tflite_test",
+        "//tfjs-tflite/src:worker_test",
     ],
 )
diff --git a/tfjs-tflite/src/BUILD.bazel b/tfjs-tflite/src/BUILD.bazel
index 07176ac7fd4..2171aeda521 100644
--- a/tfjs-tflite/src/BUILD.bazel
+++ b/tfjs-tflite/src/BUILD.bazel
@@ -15,6 +15,7 @@
 
 load("@build_bazel_rules_nodejs//:index.bzl", "copy_to_bin")
 load("//tools:defaults.bzl", "esbuild", "ts_library")
+load("//tools:tfjs_web_test.bzl", "tfjs_web_test")
 
 package(default_visibility = ["//visibility:public"])
 
@@ -55,7 +56,10 @@ copy_to_bin(
 
 ts_library(
     name = "tfjs-tflite_test_lib",
-    srcs = glob(TEST_SRCS),
+    srcs = glob(
+        TEST_SRCS,
+        exclude = ["worker_test.ts"],
+    ),
     module_name = "@tensorflow/tfjs-tflite/dist",
     deps = [
         ":tfjs-tflite_lib",
@@ -83,3 +87,46 @@ esbuild(
         "//tfjs-tflite/wasm:wasm_files",
     ],
 )
+
+ts_library(
+    name = "worker_test_lib",
+    srcs = [
+        "worker_test.ts",
+    ],
+    deps = [
+        "//tfjs-backend-cpu/src:tfjs-backend-cpu_lib",
+        "//tfjs-core/src:tfjs-core_lib",
+        "//tfjs-core/src:tfjs-core_src_lib",
+    ],
+)
+
+tfjs_web_test(
+    name = "worker_test",
+    browsers = [
+        "bs_chrome_mac",
+        "bs_firefox_mac",
+        "bs_safari_mac",
+        # Temporarily disabled because BrowserStack does not support loading
+        # absolute paths in iOS, which is required for loading the worker.
+        # https://www.browserstack.com/question/39573
+        # "bs_ios_12",
+        "bs_android_9",
+        "win_10_chrome",
+    ],
+    static_files = [
+        # For the webworker
+        "//tfjs-core:tf-core.min.js",
+        "//tfjs-core:tf-core.min.js.map",
+        "//tfjs-backend-cpu:tf-backend-cpu.min.js",
+        "//tfjs-backend-cpu:tf-backend-cpu.min.js.map",
+        "//tfjs-tflite:tf-tflite.min.js",
+        "//tfjs-tflite:tf-tflite.min.js.map",
+        "//tfjs-tflite/wasm:wasm_files",
+        "//tfjs-tflite/test_files:add4.tflite",
+    ],
+    deps = [
+        ":worker_test_lib",
+        "@npm//long:long__umd",
+        "@npm//seedrandom:seedrandom__umd",
+    ],
+)
diff --git a/tfjs-tflite/src/worker_test.ts b/tfjs-tflite/src/worker_test.ts
new file mode 100644
index 00000000000..4865470c2df
--- /dev/null
+++ b/tfjs-tflite/src/worker_test.ts
@@ -0,0 +1,60 @@
+/**
+ * @license
+ * Copyright 2022 Google LLC.
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ * http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ * =============================================================================
+ */
+
+import '@tensorflow/tfjs-backend-cpu';
+
+const str2workerURL = (str: string): string => {
+  const blob =
+      new Blob([str], {type: 'application/javascript'});
+  return URL.createObjectURL(blob);
+};
+
+// The source code of a web worker.
+const workerTest = `
+importScripts(location.origin + '/base/tfjs/tfjs-core/tf-core.min.js');
+importScripts(location.origin
+  + '/base/tfjs/tfjs-backend-cpu/tf-backend-cpu.min.js');
+// Import order matters. TFLite must be imported after tfjs core.
+importScripts(location.origin + '/base/tfjs/tfjs-tflite/tf-tflite.min.js');
+
+// Setting wasm path is required. It can be set to CDN if needed,
+// but that's not a good idea for a test.
+tflite.setWasmPath('/base/tfjs/tfjs-tflite/wasm/');
+async function main() {
+  // This is a test model that adds two tensors of shape [1, 4].
+  const model = await tflite.loadTFLiteModel(location.origin + '/base/tfjs/tfjs-tflite/test_files/add4.tflite');
+
+  const a = tf.tensor2d([[1, 2, 3, 4]]);
+  const b = tf.tensor2d([[5, 6, 7, 8]]);
+  const output = model.predict([a, b]);
+
+  self.postMessage({data: output.dataSync()});
+}
+
+main();
+`;
+
+describe('tflite in worker', () => {
+  it('runs a model', (done) => {
+    const worker = new Worker(str2workerURL(workerTest));
+    worker.onmessage = (msg) => {
+      const data = msg.data.data;
+      expect([...data]).toEqual([6, 8, 10, 12]);
+      done();
+    };
+  }, 15_000);
+});
diff --git a/tfjs-tflite/test_files/BUILD.bazel b/tfjs-tflite/test_files/BUILD.bazel
new file mode 100644
index 00000000000..ba0b9d6c0eb
--- /dev/null
+++ b/tfjs-tflite/test_files/BUILD.bazel
@@ -0,0 +1,21 @@
+# Copyright 2022 Google LLC.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+# =============================================================================
+
+package(default_visibility = ["//visibility:public"])
+
+exports_files([
+    # add4.tflite adds two tensors of shape [1,4]
+    "add4.tflite",
+])
diff --git a/tfjs-tflite/test_files/add4.tflite b/tfjs-tflite/test_files/add4.tflite
new file mode 100644
index 00000000000..6ee2860e16b
Binary files /dev/null and b/tfjs-tflite/test_files/add4.tflite differ