diff --git a/DESCRIPTION b/DESCRIPTION
index 69e413f..8b49806 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -1,6 +1,6 @@
 Package: quarto
 Title: R Interface to 'Quarto' Markdown Publishing System
-Version: 1.3.2
+Version: 1.3.3
 Authors@R: c(
     person("JJ", "Allaire", , "jj@rstudio.com", role = c("aut", "cre"),
            comment = c(ORCID = "0000-0003-0174-9868")),
diff --git a/NEWS.md b/NEWS.md
index 0e3961f..b10d269 100644
--- a/NEWS.md
+++ b/NEWS.md
@@ -1,5 +1,7 @@
 # quarto (development version)
 
+* Add `profile` arguments to `quarto_render()` and `quarto_inspect()` (thanks, #95, @andrewheiss, #123, @salim-b).
+
 * Add `metadata` and `metadata_file` to `quarto_render()` to pass modify Quarto metadata from calling render. If both are set, `metadata` will be merged over `metadata_file` content. Internally, metadata will be passed as a `--metadata-file` to `quarto render` (thanks, @mcanouil, #52, @maelle, #49).
 
 * Added a `NEWS.md` file to track changes to the package.
diff --git a/R/inspect.R b/R/inspect.R
index 963082b..f3f6788 100644
--- a/R/inspect.R
+++ b/R/inspect.R
@@ -4,12 +4,13 @@
 #' config and engines. Inspecting an input path return its formats, engine,
 #' and dependent resources.
 #'
+#' @inheritParams quarto_render
 #' @param input The input file or project directory to inspect.
 #'
-#' @return Named list. For input files, the list has members engine, format,
-#'  and resources. For projects the list has members engines and config
-#'
-#' @importFrom jsonlite fromJSON
+#' @return Named list. For input files, the list contains the elements
+#'   `quarto`, `engines`, `formats`, `resources`, plus `project` if the file is
+#'   part of a Quarto project. For projects, the list contains the elements
+#'   `quarto`, `dir`, `engines`, `config` and `files`.
 #'
 #' @examples
 #' \dontrun{
@@ -18,18 +19,26 @@
 #'
 #' # Inspect project
 #' quarto_inspect("myproject")
-#' }
 #'
+#' # Inspect project's advanced profile
+#' quarto_inspect(
+#'   input = "myproject",
+#'   profile = "advanced"
+#' )}
+#' @importFrom jsonlite fromJSON
 #' @export
-quarto_inspect <- function(input = ".") {
+quarto_inspect <- function(input = ".",
+                           profile = NULL) {
 
   quarto_bin <- find_quarto()
 
-  output <- system2(quarto_bin, stdout = TRUE, c(
-    "inspect",
-    path.expand(input)
-  ))
+  args <- c("inspect", path.expand(input))
 
-  fromJSON(output)
-}
+  if (!is.null(profile)) {
+    args <- c(args, c("--profile", paste0(profile, collapse = ",")))
+  }
+
+  res <- processx::run(quarto_bin, args, echo_cmd = getOption("quarto.echo_cmd", FALSE))
 
+  fromJSON(res$stdout)
+}
diff --git a/R/quarto-args.R b/R/quarto-args.R
new file mode 100644
index 0000000..81757c1
--- /dev/null
+++ b/R/quarto-args.R
@@ -0,0 +1,9 @@
+cli_arg_profile <- function(profile, ...) {
+  arg <- c("--profile", paste0(profile, collapse = ","))
+  append_cli_args(arg, ...)
+}
+
+append_cli_args <- function(new, append_to = NULL, after = length(append_to)) {
+  if (!is.null(append_to)) return(append(append_to, new, after))
+  new
+}
diff --git a/R/render.R b/R/render.R
index d97373c..ab3e6a9 100644
--- a/R/render.R
+++ b/R/render.R
@@ -36,6 +36,9 @@
 #'   specified, with low precedence on `metadata` options.
 #' @param debug Leave intermediate files in place after render.
 #' @param quiet Suppress warning and other messages.
+#' @param profile [Quarto project
+#'   profile(s)](https://quarto.org/docs/projects/profiles.html) to use. Either
+#'   a character vector of profile names or `NULL` to use the default profile.
 #' @param pandoc_args Additional command line options to pass to pandoc.
 #' @param as_job Render as an RStudio background job. Default is "auto",
 #'   which will render individual documents normally and projects as
@@ -76,6 +79,7 @@ quarto_render <- function(input = NULL,
                           metadata_file = NULL,
                           debug = FALSE,
                           quiet = FALSE,
+                          profile = NULL,
                           pandoc_args = NULL,
                           as_job = getOption("quarto.render_as_job", "auto")) {
 
@@ -107,7 +111,7 @@ quarto_render <- function(input = NULL,
       workingDir = getwd(),
       importEnv = TRUE
     )
-    return (invisible(NULL))
+    return(invisible(NULL))
   }
 
 
@@ -167,6 +171,9 @@ quarto_render <- function(input = NULL,
   if (isTRUE(quiet)) {
     args <- c(args, "--quiet")
   }
+  if (!is.null(profile)) {
+    args <- cli_arg_profile(profile, args)
+  }
   if (!is.null(pandoc_args)) {
     args <- c(args, pandoc_args)
   }
diff --git a/man/quarto_inspect.Rd b/man/quarto_inspect.Rd
index 4b1cd1e..ea87f96 100644
--- a/man/quarto_inspect.Rd
+++ b/man/quarto_inspect.Rd
@@ -4,14 +4,19 @@
 \alias{quarto_inspect}
 \title{Inspect Quarto Input File or Project}
 \usage{
-quarto_inspect(input = ".")
+quarto_inspect(input = ".", profile = NULL)
 }
 \arguments{
 \item{input}{The input file or project directory to inspect.}
+
+\item{profile}{\href{https://quarto.org/docs/projects/profiles.html}{Quarto project profile(s)} to use. Either
+a character vector of profile names or \code{NULL} to use the default profile.}
 }
 \value{
-Named list. For input files, the list has members engine, format,
-and resources. For projects the list has members engines and config
+Named list. For input files, the list contains the elements
+\code{quarto}, \code{engines}, \code{formats}, \code{resources}, plus \code{project} if the file is
+part of a Quarto project. For projects, the list contains the elements
+\code{quarto}, \code{dir}, \code{engines}, \code{config} and \code{files}.
 }
 \description{
 Inspect a Quarto project or input path. Inspecting a project returns its
@@ -25,6 +30,10 @@ quarto_inspect("notebook.Rmd")
 
 # Inspect project
 quarto_inspect("myproject")
-}
 
+# Inspect project's advanced profile
+quarto_inspect(
+  input = "myproject",
+  profile = "advanced"
+)}
 }
diff --git a/man/quarto_render.Rd b/man/quarto_render.Rd
index ce853c7..7d80300 100644
--- a/man/quarto_render.Rd
+++ b/man/quarto_render.Rd
@@ -21,6 +21,7 @@ quarto_render(
   metadata_file = NULL,
   debug = FALSE,
   quiet = FALSE,
+  profile = NULL,
   pandoc_args = NULL,
   as_job = getOption("quarto.render_as_job", "auto")
 )
@@ -74,6 +75,9 @@ specified, with low precedence on \code{metadata} options.}
 
 \item{quiet}{Suppress warning and other messages.}
 
+\item{profile}{\href{https://quarto.org/docs/projects/profiles.html}{Quarto project profile(s)} to use. Either
+a character vector of profile names or \code{NULL} to use the default profile.}
+
 \item{pandoc_args}{Additional command line options to pass to pandoc.}
 
 \item{as_job}{Render as an RStudio background job. Default is "auto",
diff --git a/tests/testthat/project/_quarto-test.yml b/tests/testthat/project/_quarto-test.yml
new file mode 100644
index 0000000..b42c8ff
--- /dev/null
+++ b/tests/testthat/project/_quarto-test.yml
@@ -0,0 +1,2 @@
+execute:
+  echo: true
diff --git a/tests/testthat/project/_quarto.yml b/tests/testthat/project/_quarto.yml
index b998f74..eb8af50 100644
--- a/tests/testthat/project/_quarto.yml
+++ b/tests/testthat/project/_quarto.yml
@@ -1,2 +1,5 @@
 project:
   type: site
+
+execute:
+  echo: false
diff --git a/tests/testthat/test-inspect.R b/tests/testthat/test-inspect.R
index 0df63af..74c2ffe 100644
--- a/tests/testthat/test-inspect.R
+++ b/tests/testthat/test-inspect.R
@@ -1,11 +1,22 @@
-test_that("R Markdown documents can be inspected", {
+test_that("Documents can be inspected", {
   skip_if_no_quarto()
-  metadata <- quarto_inspect("test.Rmd")
+  metadata <- quarto_inspect(test_path("test.Rmd"))
+  expect_type(metadata$formats, "list")
+  metadata <- quarto_inspect(test_path("test.qmd"))
+  expect_type(metadata$formats, "list")
+  metadata <- quarto_inspect(test_path("test.ipynb"))
   expect_type(metadata$formats, "list")
 })
 
 test_that("Quarto projects can be inspected", {
   skip_if_no_quarto()
-  metadata <- quarto_inspect("project")
+  metadata <- quarto_inspect(test_path("project"))
+  expect_type(metadata$config, "list")
+})
+
+test_that("Quarto projects can be inspected with profile", {
+  skip_if_no_quarto()
+  metadata <- quarto_inspect(test_path("project"), "test")
   expect_type(metadata$config, "list")
+  expect_identical(metadata$config$execute$echo, TRUE)
 })
diff --git a/tests/testthat/test-quarto-args.R b/tests/testthat/test-quarto-args.R
new file mode 100644
index 0000000..abfa382
--- /dev/null
+++ b/tests/testthat/test-quarto-args.R
@@ -0,0 +1,13 @@
+test_that("append to existing", {
+  expect_identical(append_cli_args("a"), "a")
+  expect_identical(append_cli_args(c("a", "b")), c("a", "b"))
+  expect_identical(append_cli_args("c", c("a", "b")), c("a", "b", "c"))
+  expect_identical(append_cli_args("b", c("a", "c"), 1), c("a", "b", "c"))
+  expect_identical(append_cli_args(c("b","c"), c("a", "d"), 1), c("a", "b", "c", "d"))
+})
+
+test_that("create profile arg", {
+  expect_identical(cli_arg_profile("a"), c("--profile", "a"))
+  expect_identical(cli_arg_profile(c("a", "b")), c("--profile", "a,b"))
+  expect_identical(cli_arg_profile(c("a", "b"), "input.qmd"), c("input.qmd", "--profile", "a,b"))
+})
diff --git a/tests/testthat/test.ipynb b/tests/testthat/test.ipynb
new file mode 100644
index 0000000..b36e93d
--- /dev/null
+++ b/tests/testthat/test.ipynb
@@ -0,0 +1,49 @@
+{
+  "cells": [
+    {
+      "cell_type": "raw",
+      "metadata": {},
+      "source": [
+        "---\n",
+        "title: \"Untitled\"\n",
+        "format: html\n",
+        "---"
+      ]
+    },
+    {
+      "cell_type": "markdown",
+      "metadata": {},
+      "source": [
+        "## Quarto\n",
+        "\n",
+        "Quarto enables you to weave together content and executable code into a finished document. To learn more about Quarto see <https://quarto.org>.\n",
+        "\n",
+        "## Running Code\n",
+        "\n",
+        "When you click the **Render** button a document will be generated that includes both content and the output of embedded code. You can embed code like this:\n",
+        "\n",
+        "```{r}\n",
+        "1 + 1\n",
+        "```\n",
+        "\n",
+        "You can add options to executable code like this\n",
+        "\n",
+        "```{r}\n",
+        "#| echo: false\n",
+        "2 * 2\n",
+        "```\n",
+        "\n",
+        "The `echo: false` option disables the printing of code (only output is displayed)."
+      ]
+    }
+  ],
+  "metadata": {
+    "kernelspec": {
+      "name": "python3",
+      "language": "python",
+      "display_name": "Python 3 (ipykernel)"
+    }
+  },
+  "nbformat": 4,
+  "nbformat_minor": 4
+}
\ No newline at end of file
diff --git a/tests/testthat/test.qmd b/tests/testthat/test.qmd
new file mode 100644
index 0000000..719c496
--- /dev/null
+++ b/tests/testthat/test.qmd
@@ -0,0 +1,25 @@
+---
+title: "Untitled"
+format: html
+---
+
+## Quarto
+
+Quarto enables you to weave together content and executable code into a finished document. To learn more about Quarto see <https://quarto.org>.
+
+## Running Code
+
+When you click the **Render** button a document will be generated that includes both content and the output of embedded code. You can embed code like this:
+
+```{r}
+1 + 1
+```
+
+You can add options to executable code like this
+
+```{r}
+#| echo: false
+2 * 2
+```
+
+The `echo: false` option disables the printing of code (only output is displayed).