diff --git a/stdlib/inspect.pyi b/stdlib/inspect.pyi
index 0c903d28d808..fdc18c919360 100644
--- a/stdlib/inspect.pyi
+++ b/stdlib/inspect.pyi
@@ -2,21 +2,15 @@ import enum
 import sys
 from _typeshed import Self
 from collections import OrderedDict
-from collections.abc import Awaitable, Callable, Generator, Mapping, Sequence, Set
-from types import (
-    AsyncGeneratorType,
-    BuiltinFunctionType,
-    CodeType,
-    CoroutineType,
-    FrameType,
-    FunctionType,
-    GeneratorType,
-    MethodType,
-    ModuleType,
-    TracebackType,
-)
-from typing import Any, ClassVar, NamedTuple, Tuple, Type, Union
-from typing_extensions import Literal, TypeGuard
+from collections.abc import AsyncGenerator, Awaitable, Callable, Coroutine, Generator, Mapping, Sequence, Set
+from types import BuiltinFunctionType, CodeType, FrameType, FunctionType, MethodType, ModuleType, TracebackType
+from typing import Any, ClassVar, NamedTuple, Tuple, Type, TypeVar, Union
+from typing_extensions import Literal, ParamSpec, TypeGuard
+
+_T = TypeVar("_T")
+_P = ParamSpec("_P")
+_SendType = TypeVar("_SendType")
+_YieldType = TypeVar("_YieldType")
 
 #
 # Types and members
@@ -48,29 +42,41 @@ TPFLAGS_IS_ABSTRACT: int
 def getmembers(object: object, predicate: Callable[[Any], bool] | None = ...) -> list[Tuple[str, Any]]: ...
 def getmodulename(path: str) -> str | None: ...
 def ismodule(object: object) -> TypeGuard[ModuleType]: ...
-def isclass(object: object) -> TypeGuard[Type[Any]]: ...
+def isclass(object: Type[_T] | object) -> TypeGuard[Type[_T]]: ...
 def ismethod(object: object) -> TypeGuard[MethodType]: ...
 def isfunction(object: object) -> TypeGuard[FunctionType]: ...
 
 if sys.version_info >= (3, 8):
-    def isgeneratorfunction(obj: object) -> bool: ...
-    def iscoroutinefunction(obj: object) -> bool: ...
+    def isgeneratorfunction(
+        obj: Callable[_P, Generator[_YieldType, _SendType, _T]] | object
+    ) -> TypeGuard[Callable[_P, Generator[_YieldType, _SendType, _T]]]: ...  # type: ignore
+    def iscoroutinefunction(
+        obj: Callable[_P, Coroutine[_YieldType, _SendType, _T]] | object
+    ) -> TypeGuard[Callable[_P, Coroutine[_YieldType, _SendType, _T]]]: ...  # type: ignore
 
 else:
-    def isgeneratorfunction(object: object) -> bool: ...
-    def iscoroutinefunction(object: object) -> bool: ...
+    def isgeneratorfunction(
+        object: Callable[_P, Generator[_YieldType, _SendType, _T]] | object
+    ) -> TypeGuard[Callable[_P, Generator[_YieldType, _SendType, _T]]]: ...  # type: ignore
+    def iscoroutinefunction(
+        object: Callable[_P, Coroutine[_YieldType, _SendType, _T]] | object
+    ) -> TypeGuard[Callable[_P, Coroutine[_YieldType, _SendType, _T]]]: ...  # type: ignore
 
-def isgenerator(object: object) -> TypeGuard[GeneratorType[Any, Any, Any]]: ...
-def iscoroutine(object: object) -> TypeGuard[CoroutineType]: ...
-def isawaitable(object: object) -> TypeGuard[Awaitable[Any]]: ...
+def isgenerator(object: Generator[_YieldType, _SendType, _T] | object) -> TypeGuard[Generator[_YieldType, _SendType, _T]]: ...
+def iscoroutine(object: Coroutine[_YieldType, _SendType, _T] | object) -> TypeGuard[Coroutine[_YieldType, _SendType, _T]]: ...
+def isawaitable(object: Awaitable[_T] | object) -> TypeGuard[Awaitable[_T]]: ...
 
 if sys.version_info >= (3, 8):
-    def isasyncgenfunction(obj: object) -> bool: ...
+    def isasyncgenfunction(
+        obj: Callable[_P, AsyncGenerator[_YieldType, _SendType]] | object
+    ) -> TypeGuard[Callable[_P, AsyncGenerator[_YieldType, _SendType]]]: ...  # type: ignore
 
 else:
-    def isasyncgenfunction(object: object) -> bool: ...
+    def isasyncgenfunction(
+        object: Callable[_P, AsyncGenerator[_YieldType, _SendType]] | object
+    ) -> TypeGuard[Callable[_P, AsyncGenerator[_YieldType, _SendType]]]: ...  # type: ignore
 
-def isasyncgen(object: object) -> TypeGuard[AsyncGeneratorType[Any, Any]]: ...
+def isasyncgen(object: AsyncGenerator[_YieldType, _SendType] | object) -> TypeGuard[AsyncGenerator[_YieldType, _SendType]]: ...
 def istraceback(object: object) -> TypeGuard[TracebackType]: ...
 def isframe(object: object) -> TypeGuard[FrameType]: ...
 def iscode(object: object) -> TypeGuard[CodeType]: ...