diff --git a/setup.cfg b/setup.cfg
index 6d02e81b62d7..74d31da11945 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -2,6 +2,13 @@
 max-line-length = 99
 # typeshed and unit test fixtures have .pyi-specific flake8 configuration
 exclude =
+  # .gitignore'd directories
+  build/*,
+  docs/build/*,
+  out/*,
+  .venv/*,
+  .cache/*,
+  .mypy_cache/*,
   # Sphinx configuration is irrelevant
   docs/source/conf.py,
   # external library with incompatible style