diff --git a/Misc/NEWS.d/next/Core_and_Builtins/2025-03-13-20-23-02.gh-issue-129149.z42wkm.rst b/Misc/NEWS.d/next/Core_and_Builtins/2025-03-13-20-23-02.gh-issue-129149.z42wkm.rst
new file mode 100644
index 00000000000000..9da77312cbb22d
--- /dev/null
+++ b/Misc/NEWS.d/next/Core_and_Builtins/2025-03-13-20-23-02.gh-issue-129149.z42wkm.rst
@@ -0,0 +1,4 @@
+Add fast path for small and medium-size integers in
+:c:func:`PyLong_FromInt32`, :c:func:`PyLong_FromUInt32`,
+:c:func:`PyLong_FromInt64` and
+:c:func:`PyLong_FromUInt64`. Patch by Chris Eibl.
diff --git a/Objects/longobject.c b/Objects/longobject.c
index 51ecbd9e0ee0bd..1c2f7f389366cf 100644
--- a/Objects/longobject.c
+++ b/Objects/longobject.c
@@ -6742,16 +6742,24 @@ PyUnstable_Long_CompactValue(const PyLongObject* op) {
 
 
 PyObject* PyLong_FromInt32(int32_t value)
-{ return PyLong_FromNativeBytes(&value, sizeof(value), -1); }
+{
+    PYLONG_FROM_INT(uint32_t, int32_t, value);
+}
 
 PyObject* PyLong_FromUInt32(uint32_t value)
-{ return PyLong_FromUnsignedNativeBytes(&value, sizeof(value), -1); }
+{
+    PYLONG_FROM_UINT(uint32_t, value);
+}
 
 PyObject* PyLong_FromInt64(int64_t value)
-{ return PyLong_FromNativeBytes(&value, sizeof(value), -1); }
+{
+    PYLONG_FROM_INT(uint64_t, int64_t, value);
+}
 
 PyObject* PyLong_FromUInt64(uint64_t value)
-{ return PyLong_FromUnsignedNativeBytes(&value, sizeof(value), -1); }
+{
+    PYLONG_FROM_UINT(uint64_t, value);
+}
 
 #define LONG_TO_INT(obj, value, type_name) \
     do { \