diff --git a/Misc/NEWS.d/next/Windows/2024-04-15-21-23-34.gh-issue-115009.uhisHP.rst b/Misc/NEWS.d/next/Windows/2024-04-15-21-23-34.gh-issue-115009.uhisHP.rst
new file mode 100644
index 00000000000000..01269b2f3e5216
--- /dev/null
+++ b/Misc/NEWS.d/next/Windows/2024-04-15-21-23-34.gh-issue-115009.uhisHP.rst
@@ -0,0 +1 @@
+Update Windows installer to use SQLite 3.45.3.
diff --git a/Misc/externals.spdx.json b/Misc/externals.spdx.json
index 8080e1f3217c6a..e905c2b907e736 100644
--- a/Misc/externals.spdx.json
+++ b/Misc/externals.spdx.json
@@ -69,21 +69,21 @@
       "checksums": [
         {
           "algorithm": "SHA256",
-          "checksumValue": "6f0364a27375435a34137b138ca4fedef8d23eec6493ca1dfff33bfc0c34fda4"
+          "checksumValue": "730e4a3efd6a63828bee499940fb13acc2a32c182502ce8a1d970387895d0504"
         }
       ],
-      "downloadLocation": "https://github.com/python/cpython-source-deps/archive/refs/tags/sqlite-3.45.1.0.tar.gz",
+      "downloadLocation": "https://github.com/python/cpython-source-deps/archive/refs/tags/sqlite-3.45.3.0.tar.gz",
       "externalRefs": [
         {
           "referenceCategory": "SECURITY",
-          "referenceLocator": "cpe:2.3:a:sqlite:sqlite:3.45.1.0:*:*:*:*:*:*:*",
+          "referenceLocator": "cpe:2.3:a:sqlite:sqlite:3.45.3.0:*:*:*:*:*:*:*",
           "referenceType": "cpe23Type"
         }
       ],
       "licenseConcluded": "NOASSERTION",
       "name": "sqlite",
       "primaryPackagePurpose": "SOURCE",
-      "versionInfo": "3.45.1.0"
+      "versionInfo": "3.45.3.0"
     },
     {
       "SPDXID": "SPDXRef-PACKAGE-tcl-core",
diff --git a/PCbuild/get_externals.bat b/PCbuild/get_externals.bat
index 79e8b391de30df..1b741d6e49f28a 100644
--- a/PCbuild/get_externals.bat
+++ b/PCbuild/get_externals.bat
@@ -54,7 +54,7 @@ set libraries=
 set libraries=%libraries%                                       bzip2-1.0.8
 if NOT "%IncludeLibffiSrc%"=="false" set libraries=%libraries%  libffi-3.4.4
 if NOT "%IncludeSSLSrc%"=="false" set libraries=%libraries%     openssl-3.0.13
-set libraries=%libraries%                                       sqlite-3.45.1.0
+set libraries=%libraries%                                       sqlite-3.45.3.0
 if NOT "%IncludeTkinterSrc%"=="false" set libraries=%libraries% tcl-core-8.6.13.0
 if NOT "%IncludeTkinterSrc%"=="false" set libraries=%libraries% tk-8.6.13.0
 if NOT "%IncludeTkinterSrc%"=="false" set libraries=%libraries% tix-8.4.3.6
diff --git a/PCbuild/python.props b/PCbuild/python.props
index d85fe4ab2a3535..d799948fa31188 100644
--- a/PCbuild/python.props
+++ b/PCbuild/python.props
@@ -68,7 +68,7 @@
   <Import Project="$(ExternalProps)" Condition="$(ExternalProps) != '' and Exists('$(ExternalProps)')" />
 
   <PropertyGroup>
-    <sqlite3Dir Condition="$(sqlite3Dir) == ''">$(ExternalsDir)sqlite-3.45.1.0\</sqlite3Dir>
+    <sqlite3Dir Condition="$(sqlite3Dir) == ''">$(ExternalsDir)sqlite-3.45.3.0\</sqlite3Dir>
     <bz2Dir Condition="$(bz2Dir) == ''">$(ExternalsDir)bzip2-1.0.8\</bz2Dir>
     <lzmaDir Condition="$(lzmaDir) == ''">$(ExternalsDir)xz-5.2.5\</lzmaDir>
     <libffiDir Condition="$(libffiDir) == ''">$(ExternalsDir)libffi-3.4.4\</libffiDir>
diff --git a/PCbuild/readme.txt b/PCbuild/readme.txt
index 178c62d3d02d2e..29edf9bf260ab1 100644
--- a/PCbuild/readme.txt
+++ b/PCbuild/readme.txt
@@ -189,7 +189,7 @@ _ssl
     again when building.
 
 _sqlite3
-    Wraps SQLite 3.45.1, which is itself built by sqlite3.vcxproj
+    Wraps SQLite 3.45.3, which is itself built by sqlite3.vcxproj
     Homepage:
         https://www.sqlite.org/
 _tkinter