diff --git a/Lib/test/libregrtest/utils.py b/Lib/test/libregrtest/utils.py
index b5bbe0ef6596a7..f62184ad4fec6c 100644
--- a/Lib/test/libregrtest/utils.py
+++ b/Lib/test/libregrtest/utils.py
@@ -184,6 +184,15 @@ def clear_caches():
         if stream is not None:
             stream.flush()
 
+    # Clear assorted module caches.
+    # Don't worry about resetting the cache if the module is not loaded
+    try:
+        distutils_dir_util = sys.modules['distutils.dir_util']
+    except KeyError:
+        pass
+    else:
+        distutils_dir_util._path_created.clear()
+
     try:
         re = sys.modules['re']
     except KeyError: