diff --git a/Misc/NEWS.d/next/Build/2018-10-26-14-49-19.bpo-35059.PKsBxP.rst b/Misc/NEWS.d/next/Build/2018-10-26-14-49-19.bpo-35059.PKsBxP.rst
new file mode 100644
index 00000000000000..262161637b1354
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2018-10-26-14-49-19.bpo-35059.PKsBxP.rst
@@ -0,0 +1,4 @@
+PCbuild: Set InlineFunctionExpansion to OnlyExplicitInline ("/Ob1" option)
+in pyproject.props in Debug mode to expand functions marked as inline. This
+change should make Python compiled in Debug mode a little bit faster on
+Windows.
diff --git a/PCbuild/pyproject.props b/PCbuild/pyproject.props
index 6d36977456e092..95b349c077e5bc 100644
--- a/PCbuild/pyproject.props
+++ b/PCbuild/pyproject.props
@@ -42,6 +42,8 @@
       <SuppressStartupBanner>true</SuppressStartupBanner>
       <WholeProgramOptimization>true</WholeProgramOptimization>
       <EnableEnhancedInstructionSet Condition="'$(Platform)'=='Win32'">NoExtensions</EnableEnhancedInstructionSet>
+      <InlineFunctionExpansion Condition="'$(Configuration)|$(Platform)'=='Debug|Win32'">OnlyExplicitInline</InlineFunctionExpansion>
+      <InlineFunctionExpansion Condition="'$(Configuration)|$(Platform)'=='Debug|x64'">OnlyExplicitInline</InlineFunctionExpansion>
     </ClCompile>
     <ClCompile Condition="$(Configuration) == 'Debug'">
       <Optimization>Disabled</Optimization>