diff --git a/Misc/NEWS.d/next/Tools-Demos/2022-12-29-19-22-11.bpo-45256.a0ee_H.rst b/Misc/NEWS.d/next/Tools-Demos/2022-12-29-19-22-11.bpo-45256.a0ee_H.rst
new file mode 100644
index 00000000000000..9c1aa57625834e
--- /dev/null
+++ b/Misc/NEWS.d/next/Tools-Demos/2022-12-29-19-22-11.bpo-45256.a0ee_H.rst
@@ -0,0 +1 @@
+Fix a bug that caused an :exc:`AttributeError` to be raised in ``python-gdb.py`` when ``py-locals`` is used without a frame.
diff --git a/Tools/gdb/libpython.py b/Tools/gdb/libpython.py
index 857e52f00a06eb..a99ce945265f67 100755
--- a/Tools/gdb/libpython.py
+++ b/Tools/gdb/libpython.py
@@ -2126,6 +2126,7 @@ def invoke(self, args, from_tty):
         while True:
             if not pyop_frame:
                 print(UNABLE_READ_INFO_PYTHON_FRAME)
+                break
 
             sys.stdout.write('Locals for %s\n' % (pyop_frame.co_name.proxyval(set())))