diff --git a/Zend/Optimizer/zend_inference.c b/Zend/Optimizer/zend_inference.c
index b7fa1e837d096..1c5e99dd30ab3 100644
--- a/Zend/Optimizer/zend_inference.c
+++ b/Zend/Optimizer/zend_inference.c
@@ -5040,7 +5040,7 @@ ZEND_API bool zend_may_throw_ex(const zend_op *opline, const zend_ssa_op *ssa_op
 			return 0;
 		case ZEND_BIND_GLOBAL:
 			if ((opline+1)->opcode == ZEND_BIND_GLOBAL) {
-				return zend_may_throw(opline + 1, ssa_op + 1, op_array, ssa);
+				return zend_may_throw(opline + 1, ssa_op ? ssa_op + 1 : NULL, op_array, ssa);
 			}
 			return 0;
 		case ZEND_ADD:
diff --git a/ext/opcache/tests/jit/gh15666.phpt b/ext/opcache/tests/jit/gh15666.phpt
new file mode 100644
index 0000000000000..090003e055abe
--- /dev/null
+++ b/ext/opcache/tests/jit/gh15666.phpt
@@ -0,0 +1,21 @@
+--TEST--
+GH-15661 (Access null pointer in Zend/Optimizer/zend_inference.c)
+--EXTENSIONS--
+opcache
+--INI--
+opcache.jit=1201
+opcache.jit_buffer_size=64M
+--FILE--
+<?php
+
+function test() {
+    require 'dummy.inc';
+    global $foo, $bar;
+    $foo |= $bar;
+}
+
+echo "Done\n";
+
+?>
+--EXPECT--
+Done