diff --git a/pandas/io/excel/_base.py b/pandas/io/excel/_base.py
index 673dbba628976..a5db36cee4254 100644
--- a/pandas/io/excel/_base.py
+++ b/pandas/io/excel/_base.py
@@ -1000,7 +1000,7 @@ def __init__(
 
         # cast ExcelWriter to avoid adding 'if self.handles is not None'
         self.handles = IOHandles(
-            cast(IO[bytes], path), compression={"copression": None}
+            cast(IO[bytes], path), compression={"compression": None}
         )
         if not isinstance(path, ExcelWriter):
             self.handles = get_handle(