diff --git a/pandas/core/frame.py b/pandas/core/frame.py
index 1a19910a0957c..5200ad0ba0d23 100644
--- a/pandas/core/frame.py
+++ b/pandas/core/frame.py
@@ -6729,14 +6729,6 @@ def apply(
         DataFrame.aggregate: Only perform aggregating type operations.
         DataFrame.transform: Only perform transforming type operations.
 
-        Notes
-        -----
-        In the current implementation apply calls `func` twice on the
-        first column/row to decide whether it can take a fast or slow
-        code path. This can lead to unexpected behavior if `func` has
-        side-effects, as they will take effect twice for the first
-        column/row.
-
         Examples
         --------