diff --git a/CHANGELOG.md b/CHANGELOG.md
index efb766bda4..1777dfa262 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -11,12 +11,14 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## Unreleased
 
+### Fixed
+- `opentelemetry-instrumentation-dbapi` Respect suppress_instrumentation functionality ([#3460](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3460))
+
 ### Breaking changes
 
 - `opentelemetry-instrumentation-botocore` Use `cloud.region` instead of `aws.region` span attribute as per semantic conventions.
   ([#3474](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3474))
 
-
 ## Version 1.33.0/0.54b0 (2025-05-09)
 
 ### Added
@@ -44,7 +46,6 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - `opentelemetry-instrumentation-botocore` Capture server attributes for botocore API calls
   ([#3448](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3448))
 
-
 ## Version 1.32.0/0.53b0 (2025-04-10)
 
 ### Added
diff --git a/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py b/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
index f87401ff32..0d1a228be1 100644
--- a/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
@@ -52,6 +52,7 @@
 from opentelemetry.instrumentation.sqlcommenter_utils import _add_sql_comment
 from opentelemetry.instrumentation.utils import (
     _get_opentelemetry_values,
+    is_instrumentation_enabled,
     unwrap,
 )
 from opentelemetry.semconv.trace import SpanAttributes
@@ -561,6 +562,9 @@ def traced_execution(
         *args: tuple[Any, ...],
         **kwargs: dict[Any, Any],
     ):
+        if not is_instrumentation_enabled():
+            return query_method(*args, **kwargs)
+
         name = self.get_operation_name(cursor, args)
         if not name:
             name = (
diff --git a/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py b/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
index 3f30f3a897..9a7a4a7d12 100644
--- a/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
@@ -21,6 +21,7 @@
 from opentelemetry import context
 from opentelemetry import trace as trace_api
 from opentelemetry.instrumentation import dbapi
+from opentelemetry.instrumentation.utils import suppress_instrumentation
 from opentelemetry.sdk import resources
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.test.test_base import TestBase
@@ -243,6 +244,21 @@ def test_no_op_tracer_provider(self):
         spans_list = self.memory_exporter.get_finished_spans()
         self.assertEqual(len(spans_list), 0)
 
+    def test_suppress_instrumentation(self):
+        db_integration = dbapi.DatabaseApiIntegration(
+            "instrumenting_module_test_name",
+            "testcomponent",
+        )
+        mock_connection = db_integration.wrapped_connection(
+            mock_connect, {}, {}
+        )
+        with suppress_instrumentation():
+            cursor = mock_connection.cursor()
+            cursor.execute("Test query", ("param1Value", False))
+
+        spans_list = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans_list), 0)
+
     def test_executemany(self):
         db_integration = dbapi.DatabaseApiIntegration(
             "instrumenting_module_test_name", "testcomponent"