diff --git a/docs/commands/mftf.md b/docs/commands/mftf.md
index aea53c96f..ac029779e 100644
--- a/docs/commands/mftf.md
+++ b/docs/commands/mftf.md
@@ -58,6 +58,14 @@ vendor/bin/mftf run:test LoginAsAdminTest LoginAsCustomerTest -r
 
 This command cleans up the previously generated tests; generates and runs the `LoginAsAdminTest` and `LoginAsCustomerTest` tests.
 
+### Generate and run a testManifest.txt file
+
+```bash
+vendor/bin/mftf run:manifest path/to/your/testManifest.txt
+```
+
+This command runs all tests specified in a `testManifest.txt` file. When you generate tests, a `testManifest.txt` file is also generated for you. You can pass this file directly to the `run:manifest` command and it will execute all listed tests. You can also create your own file in the same format to execute a subset of tests. Note: This command does not generate tests.
+
 ### Generate and run previously failed tests
 
 ```bash
@@ -338,6 +346,30 @@ Generate the `LoginCustomerTest` and `StorefrontCreateCustomerTest` tests from X
 vendor/bin/mftf run:test LoginCustomerTest StorefrontCreateCustomerTest
 ```
 
+### `run:manifest`
+
+Runs a testManifest.txt file.
+
+This command runs all tests specified in a testManifest.xml file. It does not generate tests for you. You must do that as first. 
+
+#### Usage
+
+```bash
+vendor/bin/mftf run:manifest path/to/your/testManifest.txt
+```
+
+#### Example testManifest.xml file
+
+Each line should contain either: one test path or one group (-g) reference.
+
+```
+tests/functional/tests/MFTF/_generated/default/AdminLoginTestCest.php
+-g PaypalTestSuite
+tests/functional/tests/MFTF/_generated/default/SomeOtherTestCest.php
+tests/functional/tests/MFTF/_generated/default/ThirdTestCest.php
+-g SomeOtherSuite
+```
+
 ### `run:failed`
 
 Regenerates and reruns tests that previously failed.
diff --git a/src/Magento/FunctionalTestingFramework/Console/CommandList.php b/src/Magento/FunctionalTestingFramework/Console/CommandList.php
index 5bcf1ed31..34d221840 100644
--- a/src/Magento/FunctionalTestingFramework/Console/CommandList.php
+++ b/src/Magento/FunctionalTestingFramework/Console/CommandList.php
@@ -37,6 +37,7 @@ public function __construct(array $commands = [])
              'run:test' => new RunTestCommand(),
              'run:group' => new RunTestGroupCommand(),
              'run:failed' => new RunTestFailedCommand(),
+             'run:manifest' => new RunManifestCommand(),
              'setup:env' => new SetupEnvCommand(),
              'upgrade:tests' => new UpgradeTestsCommand(),
              'generate:docs' => new GenerateDocsCommand(),
diff --git a/src/Magento/FunctionalTestingFramework/Console/RunManifestCommand.php b/src/Magento/FunctionalTestingFramework/Console/RunManifestCommand.php
new file mode 100644
index 000000000..e487d16cf
--- /dev/null
+++ b/src/Magento/FunctionalTestingFramework/Console/RunManifestCommand.php
@@ -0,0 +1,152 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+declare(strict_types = 1);
+
+namespace Magento\FunctionalTestingFramework\Console;
+
+use Magento\FunctionalTestingFramework\Exceptions\TestFrameworkException;
+use Symfony\Component\Console\Command\Command;
+use Symfony\Component\Console\Input\InputArgument;
+use Symfony\Component\Console\Input\InputInterface;
+use Symfony\Component\Console\Output\OutputInterface;
+use Symfony\Component\Process\Process;
+
+class RunManifestCommand extends Command
+{
+    /**
+     * The return code. Determined by all tests that run.
+     *
+     * @var integer
+     */
+    private $returnCode = 0;
+
+    /**
+     * A list of tests that failed.
+     * Eg: "tests/functional/tests/MFTF/_generated/default/AdminLoginTestCest.php:AdminLoginTest"
+     *
+     * @var string[]
+     */
+    private $failedTests = [];
+
+    /**
+     * Configure the run:manifest command.
+     *
+     * @return void
+     */
+    protected function configure()
+    {
+        $this->setName("run:manifest")
+            ->setDescription("runs a manifest file")
+            ->addArgument("path", InputArgument::REQUIRED, "path to a manifest file");
+    }
+
+    /**
+     * Executes the run:manifest command.
+     *
+     * @param InputInterface  $input
+     * @param OutputInterface $output
+     * @throws TestFrameworkException
+     * @return integer
+     */
+    protected function execute(InputInterface $input, OutputInterface $output): int
+    {
+        $path = $input->getArgument("path");
+
+        if (!file_exists($path)) {
+            throw new TestFrameworkException("Could not find file $path. Check the path and try again.");
+        }
+
+        $manifestFile = file($path, FILE_IGNORE_NEW_LINES);
+
+        // Delete the Codeception failed file just in case it exists from any previous test runs
+        $this->deleteFailedFile();
+
+        foreach ($manifestFile as $manifestLine) {
+            if (empty($manifestLine)) {
+                continue;
+            }
+
+            $this->runManifestLine($manifestLine, $output);
+            $this->aggregateFailed();
+        }
+
+        if (!empty($this->failedTests)) {
+            $this->deleteFailedFile();
+            $this->writeFailedFile();
+        }
+
+        return $this->returnCode;
+    }
+
+    /**
+     * Runs a test (or group) line from the manifest file
+     *
+     * @param string          $manifestLine
+     * @param OutputInterface $output
+     * @return void
+     *
+     * @SuppressWarnings(PHPMD.UnusedLocalVariable) Need this because of the unused $type variable in the closure
+     */
+    private function runManifestLine(string $manifestLine, OutputInterface $output)
+    {
+        $codeceptionCommand = realpath(PROJECT_ROOT . "/vendor/bin/codecept")
+            . " run functional --verbose --steps "
+            . $manifestLine;
+
+        // run the codecept command in a sub process
+        $process = new Process($codeceptionCommand);
+        $process->setWorkingDirectory(TESTS_BP);
+        $process->setIdleTimeout(600);
+        $process->setTimeout(0);
+        $subReturnCode = $process->run(function ($type, $buffer) use ($output) {
+            $output->write($buffer);
+        });
+        $this->returnCode = max($this->returnCode, $subReturnCode);
+    }
+
+    /**
+     * Keeps track of any tests that failed while running the manifest file.
+     *
+     * Each codecept command executions overwrites the failed file. Since we are running multiple codecept commands,
+     * we need to hold on to any failures in order to write a final failed file containing all tests.
+     *
+     * @return void
+     */
+    private function aggregateFailed()
+    {
+        if (file_exists(RunTestFailedCommand::TESTS_FAILED_FILE)) {
+            $currentFile = file(RunTestFailedCommand::TESTS_FAILED_FILE, FILE_IGNORE_NEW_LINES);
+            $this->failedTests = array_merge(
+                $this->failedTests,
+                $currentFile
+            );
+        }
+    }
+
+    /**
+     * Delete the Codeception failed file.
+     *
+     * @return void
+     */
+    private function deleteFailedFile()
+    {
+        if (file_exists(RunTestFailedCommand::TESTS_FAILED_FILE)) {
+            unlink(RunTestFailedCommand::TESTS_FAILED_FILE);
+        }
+    }
+
+    /**
+     * Writes any tests that failed to the Codeception failed file.
+     *
+     * @return void
+     */
+    private function writeFailedFile()
+    {
+        foreach ($this->failedTests as $test) {
+            file_put_contents(RunTestFailedCommand::TESTS_FAILED_FILE, $test . "\n", FILE_APPEND);
+        }
+    }
+}