diff --git a/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.cpp b/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.cpp
index 68360788c96e6..b616e99be83b2 100644
--- a/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.cpp
+++ b/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.cpp
@@ -2571,9 +2571,18 @@ Status ProcessGDBRemote::DoDestroy() {
 
   StopAsyncThread();
   KillDebugserverProcess();
+  RemoveNewThreadBreakpoints();
   return Status();
 }
 
+void ProcessGDBRemote::RemoveNewThreadBreakpoints() {
+  if (m_thread_create_bp_sp) {
+    if (TargetSP target_sp = m_target_wp.lock())
+      target_sp->RemoveBreakpointByID(m_thread_create_bp_sp->GetID());
+    m_thread_create_bp_sp.reset();
+  }
+}
+
 void ProcessGDBRemote::SetLastStopPacket(
     const StringExtractorGDBRemote &response) {
   const bool did_exec =
diff --git a/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.h b/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.h
index 1cbd1e82b381d..20d7fc0801eb3 100644
--- a/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.h
+++ b/lldb/source/Plugins/Process/gdb-remote/ProcessGDBRemote.h
@@ -436,6 +436,9 @@ class ProcessGDBRemote : public Process,
                                            lldb::user_id_t break_id,
                                            lldb::user_id_t break_loc_id);
 
+  /// Remove the breakpoints associated with thread creation from the Target.
+  void RemoveNewThreadBreakpoints();
+
   // ContinueDelegate interface
   void HandleAsyncStdout(llvm::StringRef out) override;
   void HandleAsyncMisc(llvm::StringRef data) override;
diff --git a/lldb/test/API/macosx/thread_start_bps/TestBreakpointsThreadInit.py b/lldb/test/API/macosx/thread_start_bps/TestBreakpointsThreadInit.py
index 1c6fd4f91c73e..bf667f6f7d336 100644
--- a/lldb/test/API/macosx/thread_start_bps/TestBreakpointsThreadInit.py
+++ b/lldb/test/API/macosx/thread_start_bps/TestBreakpointsThreadInit.py
@@ -35,3 +35,23 @@ def test_internal_bps_resolved(self):
         for bp in bps:
             num_resolved += bp.GetNumResolvedLocations()
         self.assertGreater(num_resolved, 0)
+
+    @skipUnlessDarwin
+    def test_internal_bps_deleted_on_relaunch(self):
+        self.build()
+
+        source_file = lldb.SBFileSpec("main.c")
+        target, process, thread, bkpt = lldbutil.run_to_source_breakpoint(
+            self, "initial hello", source_file
+        )
+
+        self.runCmd("break list --internal")
+        output = self.res.GetOutput()
+        self.assertEqual(output.count("thread-creation"), 1)
+
+        process.Kill()
+        self.runCmd("run", RUN_SUCCEEDED)
+
+        self.runCmd("break list --internal")
+        output = self.res.GetOutput()
+        self.assertEqual(output.count("thread-creation"), 1)