diff --git a/google/cloud/bigquery/client.py b/google/cloud/bigquery/client.py
index ea592852a..c50e7c2d7 100644
--- a/google/cloud/bigquery/client.py
+++ b/google/cloud/bigquery/client.py
@@ -139,7 +139,7 @@
 
 if typing.TYPE_CHECKING:  # pragma: NO COVER
     # os.PathLike is only subscriptable in Python 3.9+, thus shielding with a condition.
-    PathType = Union[str, bytes, os.PathLike[str], os.PathLike[bytes]]
+    PathType = Union[str, bytes, os.PathLike[str], os.PathLike[bytes], io.IOBase]
 _DEFAULT_CHUNKSIZE = 100 * 1024 * 1024  # 100 MB
 _MAX_MULTIPART_SIZE = 5 * 1024 * 1024
 _DEFAULT_NUM_RETRIES = 6