diff --git a/bigframes/core/compile/sqlglot/compiler.py b/bigframes/core/compile/sqlglot/compiler.py
index 93f072973c..ff2bb32e3c 100644
--- a/bigframes/core/compile/sqlglot/compiler.py
+++ b/bigframes/core/compile/sqlglot/compiler.py
@@ -242,6 +242,28 @@ def compile_join(
             joins_nulls=node.joins_nulls,
         )
 
+    @_compile_node.register
+    def compile_isin_join(
+        self, node: nodes.InNode, left: ir.SQLGlotIR, right: ir.SQLGlotIR
+    ) -> ir.SQLGlotIR:
+        conditions = tuple(
+            typed_expr.TypedExpr(
+                scalar_compiler.compile_scalar_expression(node.left_col),
+                left.output_type,
+            ),
+            typed_expr.TypedExpr(
+                scalar_compiler.compile_scalar_expression(node.right_col),
+                right.output_type,
+            ),
+        )
+
+        return left.isin_join(
+            right,
+            indicator_col=node.indicator_col.sql,
+            conditions=conditions,
+            joins_nulls=node.joins_nulls,
+        )
+
     @_compile_node.register
     def compile_concat(
         self, node: nodes.ConcatNode, *children: ir.SQLGlotIR
diff --git a/bigframes/core/compile/sqlglot/sqlglot_ir.py b/bigframes/core/compile/sqlglot/sqlglot_ir.py
index c0bed4090c..ffdbab8b79 100644
--- a/bigframes/core/compile/sqlglot/sqlglot_ir.py
+++ b/bigframes/core/compile/sqlglot/sqlglot_ir.py
@@ -332,6 +332,56 @@ def join(
 
         return SQLGlotIR(expr=new_expr, uid_gen=self.uid_gen)
 
+    def isin_join(
+        self,
+        right: SQLGlotIR,
+        indicator_col: str,
+        conditions: tuple[typed_expr.TypedExpr, typed_expr.TypedExpr],
+        *,
+        joins_nulls: bool = True,
+    ) -> SQLGlotIR:
+        """Joins the current query with another SQLGlotIR instance."""
+        # TODO: Optimization similar to Ibis:
+        # if isinstance(values, ArrayValue):
+        #     return ops.ArrayContains(values, self).to_expr()
+        # elif isinstance(values, Column):
+        #     return ops.InSubquery(values.as_table(), needle=self).to_expr()
+        # else:
+        #     return ops.InValues(self, values).to_expr()
+    
+        raise NotImplementedError
+        # left_cte_name = sge.to_identifier(
+        #     next(self.uid_gen.get_uid_stream("bfcte_")), quoted=self.quoted
+        # )
+        # right_cte_name = sge.to_identifier(
+        #     next(self.uid_gen.get_uid_stream("bfcte_")), quoted=self.quoted
+        # )
+
+        # left_select = _select_to_cte(self.expr, left_cte_name)
+        # right_select = _select_to_cte(right.expr, right_cte_name)
+
+        # left_ctes = left_select.args.pop("with", [])
+        # right_ctes = right_select.args.pop("with", [])
+        # merged_ctes = [*left_ctes, *right_ctes]
+
+
+
+        # join_conditions = [
+        #     _join_condition(left, right, joins_nulls) for left, right in conditions
+        # ]
+        # join_on = sge.And(expressions=join_conditions) if join_conditions else None
+
+        # join_type_str = join_type if join_type != "outer" else "full outer"
+        # new_expr = (
+        #     sge.Select()
+        #     .select(sge.Star())
+        #     .from_(sge.Table(this=left_cte_name))
+        #     .join(sge.Table(this=right_cte_name), on=join_on, join_type=join_type_str)
+        # )
+        # new_expr.set("with", sge.With(expressions=merged_ctes))
+
+        # return SQLGlotIR(expr=new_expr, uid_gen=self.uid_gen)
+
     def explode(
         self,
         column_names: tuple[str, ...],
diff --git a/tests/unit/core/compile/sqlglot/snapshots/test_compile_isin/test_compile_isin/out.sql b/tests/unit/core/compile/sqlglot/snapshots/test_compile_isin/test_compile_isin/out.sql
new file mode 100644
index 0000000000..b9cced3226
--- /dev/null
+++ b/tests/unit/core/compile/sqlglot/snapshots/test_compile_isin/test_compile_isin/out.sql
@@ -0,0 +1,10 @@
+WITH `bfcte_0` AS (
+  SELECT
+    *
+  FROM UNNEST(ARRAY<STRUCT<`bfcol_0` FLOAT64, `bfcol_1` INT64>>[STRUCT(314159.0, 0), STRUCT(2.0, 1), STRUCT(3.0, 2), STRUCT(CAST(NULL AS FLOAT64), 3)])
+)
+SELECT
+  `bfcol_0` AS `0`
+FROM `bfcte_0`
+ORDER BY
+  `bfcol_1` ASC NULLS LAST
\ No newline at end of file
diff --git a/tests/unit/core/compile/sqlglot/test_compile_isin.py b/tests/unit/core/compile/sqlglot/test_compile_isin.py
new file mode 100644
index 0000000000..6a022873d2
--- /dev/null
+++ b/tests/unit/core/compile/sqlglot/test_compile_isin.py
@@ -0,0 +1,30 @@
+# Copyright 2025 Google LLC
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import pandas as pd
+import pytest
+
+import bigframes
+import bigframes.pandas as bpd
+
+pytest.importorskip("pytest_snapshot")
+
+
+def test_compile_isin(
+    scalar_types_df: bpd.DataFrame, compiler_session: bigframes.Session, snapshot
+):
+    data = [314159, 2.0, 3, pd.NA]
+    s = bpd.Series(data, session=compiler_session)
+    bf_isin = scalar_types_df["int64_col"].isin(s).to_frame()
+    snapshot.assert_match(bf_isin.sql, "out.sql")