diff --git a/packages/node/src/integrations/http.ts b/packages/node/src/integrations/http.ts
index b95faf58d848..4cdd58f7ee25 100644
--- a/packages/node/src/integrations/http.ts
+++ b/packages/node/src/integrations/http.ts
@@ -72,6 +72,7 @@ export class Http implements Integration {
 
     // Do not auto-instrument for other instrumenter
     if (clientOptions && clientOptions.instrumenter !== 'sentry') {
+      __DEBUG_BUILD__ && logger.log('HTTP Integration is skipped because of instrumenter configuration.');
       return;
     }
 
diff --git a/packages/node/test/integrations/http.test.ts b/packages/node/test/integrations/http.test.ts
index 4f5205f0b596..6bf8a7117327 100644
--- a/packages/node/test/integrations/http.test.ts
+++ b/packages/node/test/integrations/http.test.ts
@@ -2,7 +2,7 @@ import * as sentryCore from '@sentry/core';
 import { Hub } from '@sentry/core';
 import { addExtensionMethods, Span, TRACEPARENT_REGEXP, Transaction } from '@sentry/tracing';
 import { TransactionContext } from '@sentry/types';
-import { parseSemver } from '@sentry/utils';
+import { logger, parseSemver } from '@sentry/utils';
 import * as http from 'http';
 import * as https from 'https';
 import * as HttpsProxyAgent from 'https-proxy-agent';
@@ -188,6 +188,28 @@ describe('tracing', () => {
     expect(transaction.metadata.propagations).toBe(2);
   });
 
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const options = getDefaultNodeClientOptions({
+      dsn: 'https://dogsarebadatkeepingsecrets@squirrelchasers.ingest.sentry.io/12312012',
+      tracesSampleRate: 1.0,
+      integrations: [new HttpIntegration({ tracing: true })],
+      release: '1.0.0',
+      environment: 'production',
+      instrumenter: 'otel',
+    });
+    const hub = new Hub(new NodeClient(options));
+
+    const integration = new HttpIntegration();
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('HTTP Integration is skipped because of instrumenter configuration.');
+  });
+
   describe('tracePropagationTargets option', () => {
     beforeEach(() => {
       // hacky way of restoring monkey patched functions
diff --git a/packages/tracing/test/integrations/apollo.test.ts b/packages/tracing/test/integrations/apollo.test.ts
index 2f8e5c843d07..8b9946ba4a70 100644
--- a/packages/tracing/test/integrations/apollo.test.ts
+++ b/packages/tracing/test/integrations/apollo.test.ts
@@ -1,8 +1,10 @@
 /* eslint-disable @typescript-eslint/unbound-method */
 import { Hub, Scope } from '@sentry/core';
+import { logger } from '@sentry/utils';
 
 import { Apollo } from '../../src/integrations/node/apollo';
 import { Span } from '../../src/span';
+import { getTestClient } from '../testutils';
 
 type ApolloResolverGroup = {
   [key: string]: () => any;
@@ -100,4 +102,19 @@ describe('setupOnce', () => {
     });
     expect(childSpan.finish).toBeCalled();
   });
+
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const client = getTestClient({ instrumenter: 'otel' });
+    const hub = new Hub(client);
+
+    const integration = new Apollo();
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('Apollo Integration is skipped because of instrumenter configuration.');
+  });
 });
diff --git a/packages/tracing/test/integrations/graphql.test.ts b/packages/tracing/test/integrations/graphql.test.ts
index e074dfc602f8..265bbe0fb0d8 100644
--- a/packages/tracing/test/integrations/graphql.test.ts
+++ b/packages/tracing/test/integrations/graphql.test.ts
@@ -1,8 +1,10 @@
 /* eslint-disable @typescript-eslint/unbound-method */
 import { Hub, Scope } from '@sentry/core';
+import { logger } from '@sentry/utils';
 
 import { GraphQL } from '../../src/integrations/node/graphql';
 import { Span } from '../../src/span';
+import { getTestClient } from '../testutils';
 
 const GQLExecute = {
   execute() {
@@ -53,4 +55,19 @@ describe('setupOnce', () => {
     expect(childSpan.finish).toBeCalled();
     expect(scope.setSpan).toHaveBeenCalledTimes(2);
   });
+
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const client = getTestClient({ instrumenter: 'otel' });
+    const hub = new Hub(client);
+
+    const integration = new GraphQL();
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('GraphQL Integration is skipped because of instrumenter configuration.');
+  });
 });
diff --git a/packages/tracing/test/integrations/node/mongo.test.ts b/packages/tracing/test/integrations/node/mongo.test.ts
index b7417a6ae9b2..e362db6f0c47 100644
--- a/packages/tracing/test/integrations/node/mongo.test.ts
+++ b/packages/tracing/test/integrations/node/mongo.test.ts
@@ -1,8 +1,10 @@
 /* eslint-disable @typescript-eslint/unbound-method */
 import { Hub, Scope } from '@sentry/core';
+import { logger } from '@sentry/utils';
 
 import { Mongo } from '../../../src/integrations/node/mongo';
 import { Span } from '../../../src/span';
+import { getTestClient } from '../../testutils';
 
 class Collection {
   public collectionName: string = 'mockedCollectionName';
@@ -111,4 +113,19 @@ describe('patchOperation()', () => {
     });
     expect(childSpan.finish).toBeCalled();
   });
+
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const client = getTestClient({ instrumenter: 'otel' });
+    const hub = new Hub(client);
+
+    const integration = new Mongo();
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('Mongo Integration is skipped because of instrumenter configuration.');
+  });
 });
diff --git a/packages/tracing/test/integrations/node/postgres.test.ts b/packages/tracing/test/integrations/node/postgres.test.ts
index 4b6c23db41e6..2ef3754b28ef 100644
--- a/packages/tracing/test/integrations/node/postgres.test.ts
+++ b/packages/tracing/test/integrations/node/postgres.test.ts
@@ -1,8 +1,10 @@
 /* eslint-disable @typescript-eslint/unbound-method */
 import { Hub, Scope } from '@sentry/core';
+import { logger } from '@sentry/utils';
 
 import { Postgres } from '../../../src/integrations/node/postgres';
 import { Span } from '../../../src/span';
+import { getTestClient } from '../../testutils';
 
 class PgClient {
   // https://node-postgres.com/api/client#clientquery
@@ -94,4 +96,19 @@ describe('setupOnce', () => {
       expect(childSpan.finish).toBeCalled();
     });
   });
+
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const client = getTestClient({ instrumenter: 'otel' });
+    const hub = new Hub(client);
+
+    const integration = new Postgres();
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('Postgres Integration is skipped because of instrumenter configuration.');
+  });
 });
diff --git a/packages/tracing/test/integrations/node/prisma.test.ts b/packages/tracing/test/integrations/node/prisma.test.ts
index 3c088ac25834..d2adb685fc9d 100644
--- a/packages/tracing/test/integrations/node/prisma.test.ts
+++ b/packages/tracing/test/integrations/node/prisma.test.ts
@@ -1,8 +1,10 @@
 /* eslint-disable @typescript-eslint/unbound-method */
 import { Hub, Scope } from '@sentry/core';
+import { logger } from '@sentry/utils';
 
 import { Prisma } from '../../../src/integrations/node/prisma';
 import { Span } from '../../../src/span';
+import { getTestClient } from '../../testutils';
 
 type PrismaMiddleware = (params: unknown, next: (params?: unknown) => Promise<unknown>) => Promise<unknown>;
 
@@ -30,7 +32,6 @@ describe('setupOnce', function () {
   let childSpan: Span;
 
   beforeAll(() => {
-    // @ts-ignore, not to export PrismaClient types from integration source
     new Prisma({ client: Client }).setupOnce(
       () => undefined,
       () => new Hub(undefined, scope),
@@ -58,4 +59,19 @@ describe('setupOnce', function () {
       done();
     });
   });
+
+  it("doesn't attach when using otel instrumenter", () => {
+    const loggerLogSpy = jest.spyOn(logger, 'log');
+
+    const client = getTestClient({ instrumenter: 'otel' });
+    const hub = new Hub(client);
+
+    const integration = new Prisma({ client: Client });
+    integration.setupOnce(
+      () => {},
+      () => hub,
+    );
+
+    expect(loggerLogSpy).toBeCalledWith('Prisma Integration is skipped because of instrumenter configuration.');
+  });
 });
diff --git a/packages/tracing/test/testutils.ts b/packages/tracing/test/testutils.ts
index 474eb57846f4..4ddd042a1240 100644
--- a/packages/tracing/test/testutils.ts
+++ b/packages/tracing/test/testutils.ts
@@ -1,5 +1,5 @@
 import { createTransport } from '@sentry/browser';
-import { ClientOptions } from '@sentry/types';
+import { Client, ClientOptions } from '@sentry/types';
 import { GLOBAL_OBJ, resolvedSyncPromise } from '@sentry/utils';
 import { JSDOM } from 'jsdom';
 
@@ -66,3 +66,19 @@ export function getDefaultBrowserClientOptions(options: Partial<ClientOptions> =
     ...options,
   };
 }
+
+export function getTestClient(options: Partial<ClientOptions>): Client {
+  class TestClient {
+    _options: Partial<ClientOptions>;
+
+    constructor(options: Partial<ClientOptions>) {
+      this._options = options;
+    }
+
+    getOptions(): Partial<ClientOptions> {
+      return this._options;
+    }
+  }
+
+  return new TestClient(options) as unknown as Client;
+}