diff --git a/packages/browser/src/exports.ts b/packages/browser/src/exports.ts
index e9e947de8559..93677f34fa82 100644
--- a/packages/browser/src/exports.ts
+++ b/packages/browser/src/exports.ts
@@ -111,4 +111,4 @@ export { linkedErrorsIntegration } from './integrations/linkederrors';
 export { browserApiErrorsIntegration } from './integrations/trycatch';
 
 // eslint-disable-next-line deprecation/deprecation
-export { GlobalHandlers, TryCatch, Breadcrumbs, LinkedErrors, HttpContext, Dedupe } from './integrations';
+export { TryCatch, Breadcrumbs, LinkedErrors, HttpContext, Dedupe } from './integrations';
diff --git a/packages/browser/src/integrations/globalhandlers.ts b/packages/browser/src/integrations/globalhandlers.ts
index c1096e7c2132..e2aa0b6116f0 100644
--- a/packages/browser/src/integrations/globalhandlers.ts
+++ b/packages/browser/src/integrations/globalhandlers.ts
@@ -1,19 +1,9 @@
-/* eslint-disable @typescript-eslint/no-unsafe-member-access */
-import { captureEvent, convertIntegrationFnToClass, defineIntegration, getClient } from '@sentry/core';
-import type {
-  Client,
-  Event,
-  Integration,
-  IntegrationClass,
-  IntegrationFn,
-  Primitive,
-  StackParser,
-} from '@sentry/types';
+import { captureEvent, defineIntegration, getClient } from '@sentry/core';
+import type { Client, Event, IntegrationFn, Primitive, StackParser } from '@sentry/types';
 import {
   addGlobalErrorInstrumentationHandler,
   addGlobalUnhandledRejectionInstrumentationHandler,
   getLocationHref,
-  isErrorEvent,
   isPrimitive,
   isString,
   logger,
@@ -57,18 +47,6 @@ const _globalHandlersIntegration = ((options: Partial<GlobalHandlersIntegrations
 
 export const globalHandlersIntegration = defineIntegration(_globalHandlersIntegration);
 
-/**
- * Global handlers.
- * @deprecated Use `globalHandlersIntegration()` instead.
- */
-// eslint-disable-next-line deprecation/deprecation
-export const GlobalHandlers = convertIntegrationFnToClass(
-  INTEGRATION_NAME,
-  globalHandlersIntegration,
-) as IntegrationClass<Integration & { setup: (client: Client) => void }> & {
-  new (options?: Partial<GlobalHandlersIntegrations>): Integration;
-};
-
 function _installGlobalOnErrorHandler(client: Client): void {
   addGlobalErrorInstrumentationHandler(data => {
     const { stackParser, attachStacktrace } = getOptions();
@@ -79,15 +57,12 @@ function _installGlobalOnErrorHandler(client: Client): void {
 
     const { msg, url, line, column, error } = data;
 
-    const event =
-      error === undefined && isString(msg)
-        ? _eventFromIncompleteOnError(msg, url, line, column)
-        : _enhanceEventWithInitialFrame(
-            eventFromUnknownInput(stackParser, error || msg, undefined, attachStacktrace, false),
-            url,
-            line,
-            column,
-          );
+    const event = _enhanceEventWithInitialFrame(
+      eventFromUnknownInput(stackParser, error || msg, undefined, attachStacktrace, false),
+      url,
+      line,
+      column,
+    );
 
     event.level = 'error';
 
@@ -132,24 +107,23 @@ function _getUnhandledRejectionError(error: unknown): unknown {
     return error;
   }
 
-  // eslint-disable-next-line @typescript-eslint/no-explicit-any
-  const e = error as any;
-
   // dig the object of the rejection out of known event types
   try {
+    type ErrorWithReason = { reason: unknown };
     // PromiseRejectionEvents store the object of the rejection under 'reason'
     // see https://developer.mozilla.org/en-US/docs/Web/API/PromiseRejectionEvent
-    if ('reason' in e) {
-      return e.reason;
+    if ('reason' in (error as ErrorWithReason)) {
+      return (error as ErrorWithReason).reason;
     }
 
+    type CustomEventWithDetail = { detail: { reason: unknown } };
     // something, somewhere, (likely a browser extension) effectively casts PromiseRejectionEvents
     // to CustomEvents, moving the `promise` and `reason` attributes of the PRE into
     // the CustomEvent's `detail` attribute, since they're not part of CustomEvent's spec
     // see https://developer.mozilla.org/en-US/docs/Web/API/CustomEvent and
     // https://github.com/getsentry/sentry-javascript/issues/2380
-    else if ('detail' in e && 'reason' in e.detail) {
-      return e.detail.reason;
+    if ('detail' in (error as CustomEventWithDetail) && 'reason' in (error as CustomEventWithDetail).detail) {
+      return (error as CustomEventWithDetail).detail.reason;
     }
   } catch {} // eslint-disable-line no-empty
 
@@ -176,38 +150,6 @@ function _eventFromRejectionWithPrimitive(reason: Primitive): Event {
   };
 }
 
-/**
- * This function creates a stack from an old, error-less onerror handler.
- */
-// eslint-disable-next-line @typescript-eslint/no-explicit-any
-function _eventFromIncompleteOnError(msg: any, url: any, line: any, column: any): Event {
-  const ERROR_TYPES_RE =
-    /^(?:[Uu]ncaught (?:exception: )?)?(?:((?:Eval|Internal|Range|Reference|Syntax|Type|URI|)Error): )?(.*)$/i;
-
-  // If 'message' is ErrorEvent, get real message from inside
-  let message = isErrorEvent(msg) ? msg.message : msg;
-  let name = 'Error';
-
-  const groups = message.match(ERROR_TYPES_RE);
-  if (groups) {
-    name = groups[1];
-    message = groups[2];
-  }
-
-  const event = {
-    exception: {
-      values: [
-        {
-          type: name,
-          value: message,
-        },
-      ],
-    },
-  };
-
-  return _enhanceEventWithInitialFrame(event, url, line, column);
-}
-
 // eslint-disable-next-line @typescript-eslint/no-explicit-any
 function _enhanceEventWithInitialFrame(event: Event, url: any, line: any, column: any): Event {
   // event.exception
diff --git a/packages/browser/src/integrations/index.ts b/packages/browser/src/integrations/index.ts
index 17ac85b31232..977cdabba8a4 100644
--- a/packages/browser/src/integrations/index.ts
+++ b/packages/browser/src/integrations/index.ts
@@ -1,5 +1,4 @@
 /* eslint-disable deprecation/deprecation */
-export { GlobalHandlers } from './globalhandlers';
 export { TryCatch } from './trycatch';
 export { Breadcrumbs } from './breadcrumbs';
 export { LinkedErrors } from './linkederrors';