diff --git a/src/Components/Web.JS/src/Platform/Mono/MonoPlatform.ts b/src/Components/Web.JS/src/Platform/Mono/MonoPlatform.ts
index 5a6904f841b1..027a6260a66e 100644
--- a/src/Components/Web.JS/src/Platform/Mono/MonoPlatform.ts
+++ b/src/Components/Web.JS/src/Platform/Mono/MonoPlatform.ts
@@ -356,6 +356,7 @@ function createEmscriptenModuleInstance(resourceLoader: WebAssemblyResourceLoade
     resourceLoader.purgeUnusedCacheEntriesAsync(); // Don't await - it's fine to run in background
 
     MONO.mono_wasm_setenv("MONO_URI_DOTNETRELATIVEORABSOLUTE", "true");
+    MONO.mono_wasm_setenv("DOTNET_SYSTEM_GLOBALIZATION_INVARIANT", "1");
     const load_runtime = cwrap('mono_wasm_load_runtime', null, ['string', 'number']);
     // -1 enables debugging with logging disabled. 0 disables debugging entirely.
     load_runtime(appBinDirName, hasDebuggingEnabled() ? -1 : 0);