diff --git a/dwds/CHANGELOG.md b/dwds/CHANGELOG.md
index c85939924..e87b3ff5a 100644
--- a/dwds/CHANGELOG.md
+++ b/dwds/CHANGELOG.md
@@ -1,3 +1,9 @@
+## Unreleased
+
+- Add support for the Dart Development Service (DDS). Introduces 'single
+  client mode', which prevents additional direct connections to DWDS when
+  DDS is connected.
+
 ## 6.0.0
 
 - Depend on the latest `package:devtools` and `package:devtools_server`.
diff --git a/dwds/lib/src/dwds_vm_client.dart b/dwds/lib/src/dwds_vm_client.dart
index 23194d1ee..805e4df16 100644
--- a/dwds/lib/src/dwds_vm_client.dart
+++ b/dwds/lib/src/dwds_vm_client.dart
@@ -21,6 +21,9 @@ class DwdsVmClient {
   final StreamController<Map<String, Object>> _requestController;
   final StreamController<Map<String, Object>> _responseController;
 
+  static const int kFeatureDisabled = 100;
+  static const String kFeatureDisabledMessage = 'Feature is disabled.';
+
   /// Null until [close] is called.
   ///
   /// All subsequent calls to [close] will return this future.
@@ -100,6 +103,28 @@ class DwdsVmClient {
     });
     await client.registerService('ext.dwds.screenshot', 'DWDS');
 
+    client.registerServiceCallback('_yieldControlToDDS', (request) async {
+      final ddsUri = request['uri'] as String;
+      if (ddsUri == null) {
+        return RPCError(
+          request['method'] as String,
+          RPCError.kInvalidParams,
+          "'Missing parameter: 'uri'",
+        ).toMap();
+      }
+      return DebugService.yieldControlToDDS(ddsUri)
+          ? {'result': Success().toJson()}
+          : {
+              'error': {
+                'code': kFeatureDisabled,
+                'message': kFeatureDisabledMessage,
+                'details':
+                    'Existing VM service clients prevent DDS from taking control.',
+              },
+            };
+    });
+    await client.registerService('_yieldControlToDDS', 'DWDS');
+
     return DwdsVmClient(client, requestController, responseController);
   }
 }
diff --git a/dwds/lib/src/services/debug_service.dart b/dwds/lib/src/services/debug_service.dart
index c0b59d4e7..78db366a8 100644
--- a/dwds/lib/src/services/debug_service.dart
+++ b/dwds/lib/src/services/debug_service.dart
@@ -27,6 +27,9 @@ import '../utilities/shared.dart';
 import 'chrome_proxy_service.dart';
 import 'expression_compiler.dart';
 
+bool _acceptNewConnections = true;
+int _clientsConnected = 0;
+
 void Function(WebSocketChannel, String) _createNewConnectionHandler(
   ChromeProxyService chromeProxyService,
   ServiceExtensionRegistry serviceExtensionRegistry, {
@@ -51,9 +54,18 @@ void Function(WebSocketChannel, String) _createNewConnectionHandler(
       if (onRequest != null) onRequest(request);
       return request;
     });
-
+    ++_clientsConnected;
     VmServerConnection(inputStream, responseController.sink,
-        serviceExtensionRegistry, chromeProxyService);
+            serviceExtensionRegistry, chromeProxyService)
+        .done
+        .whenComplete(() async {
+      --_clientsConnected;
+      if (!_acceptNewConnections && _clientsConnected == 0) {
+        // DDS has disconnected so we can allow for clients to connect directly
+        // to DWDS.
+        _acceptNewConnections = true;
+      }
+    });
   };
 }
 
@@ -80,9 +92,18 @@ Future<void> _handleSseConnections(
       if (onRequest != null) onRequest(request);
       return request;
     });
+    ++_clientsConnected;
     var vmServerConnection = VmServerConnection(inputStream,
         responseController.sink, serviceExtensionRegistry, chromeProxyService);
-    unawaited(vmServerConnection.done.whenComplete(sub.cancel));
+    unawaited(vmServerConnection.done.whenComplete(() {
+      --_clientsConnected;
+      if (!_acceptNewConnections && _clientsConnected == 0) {
+        // DDS has disconnected so we can allow for clients to connect directly
+        // to DWDS.
+        _acceptNewConnections = true;
+      }
+      return sub.cancel();
+    }));
   }
 }
 
@@ -90,6 +111,8 @@ Future<void> _handleSseConnections(
 ///
 /// Creates a [ChromeProxyService] from an existing Chrome instance.
 class DebugService {
+  static String _ddsUri;
+
   final VmServiceInterface chromeProxyService;
   final String hostname;
   final ServiceExtensionRegistry serviceExtensionRegistry;
@@ -124,6 +147,15 @@ class DebugService {
       : Uri(scheme: 'ws', host: hostname, port: port, path: '$_authToken')
           .toString();
 
+  static bool yieldControlToDDS(String uri) {
+    if (_clientsConnected > 1) {
+      return false;
+    }
+    _ddsUri = uri;
+    _acceptNewConnections = false;
+    return true;
+  }
+
   static Future<DebugService> start(
       String hostname,
       RemoteDebugger remoteDebugger,
@@ -163,6 +195,13 @@ class DebugService {
           chromeProxyService, serviceExtensionRegistry,
           onRequest: onRequest, onResponse: onResponse));
       handler = (shelf.Request request) {
+        if (!_acceptNewConnections) {
+          return shelf.Response.forbidden(
+            'Cannot connect directly to the VM service as a Dart Development '
+            'Service (DDS) instance has taken control and can be found at '
+            '$_ddsUri.',
+          );
+        }
         if (request.url.pathSegments.first != authToken) {
           return shelf.Response.forbidden('Incorrect auth token');
         }
diff --git a/dwds/test/debug_service_test.dart b/dwds/test/debug_service_test.dart
index efabf0e64..47f177a4f 100644
--- a/dwds/test/debug_service_test.dart
+++ b/dwds/test/debug_service_test.dart
@@ -3,6 +3,8 @@
 // BSD-style license that can be found in the LICENSE file.
 
 @TestOn('vm')
+import 'dart:async';
+import 'dart:convert';
 import 'dart:io';
 
 import 'package:test/test.dart';
@@ -27,6 +29,46 @@ void main() {
   });
 
   test('Accepts connections with the auth token', () async {
-    expect(WebSocket.connect('${context.debugConnection.uri}/ws'), completes);
+    expect(
+        WebSocket.connect('${context.debugConnection.uri}/ws')
+            .then((ws) => ws.close()),
+        completes);
+  });
+
+  test('Refuses additional connections when in single client mode', () async {
+    final ddsWs = await WebSocket.connect(
+      '${context.debugConnection.uri}/ws',
+    );
+    final completer = Completer<void>();
+    ddsWs.listen((event) {
+      final response = json.decode(event as String);
+      expect(response['id'], '0');
+      expect(response.containsKey('result'), isTrue);
+      final result = response['result'] as Map<String, dynamic>;
+      expect(result['type'], 'Success');
+      completer.complete();
+    });
+
+    const yieldControlToDDS = <String, dynamic>{
+      'jsonrpc': '2.0',
+      'id': '0',
+      'method': '_yieldControlToDDS',
+      'params': {
+        'uri': 'http://localhost:123',
+      },
+    };
+    ddsWs.add(json.encode(yieldControlToDDS));
+    await completer.future;
+
+    // While DDS is connected, expect additional connections to fail.
+    await expectLater(WebSocket.connect('${context.debugConnection.uri}/ws'),
+        throwsA(isA<WebSocketException>()));
+
+    // However, once DDS is disconnected, additional clients can connect again.
+    await ddsWs.close();
+    expect(
+        WebSocket.connect('${context.debugConnection.uri}/ws')
+            .then((ws) => ws.close()),
+        completes);
   });
 }