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GSoC 2025 biodynamo introduction blog and contributor profile
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_data/contributors.yml

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proposal: /assets/docs/Aditya_Pandey_GSoC2025.pdf
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mentors: Martin Vassilev, Jonas Rembser, Fons Rademakers, Vassil Vassilev
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- name: Salvador de la Torre Gonzalez
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info: "Google Summer of Code 2025 Contributor"
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photo: salva_de_la_torre_gonzalez.jpg
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github: "https://github.com/salva24"
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linkedin: "https://www.linkedin.com/in/salva-de-la-torre-gonzalez-7299b6335/"
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education: "Mathematics and Computer Engineering, University of Seville, Spain"
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active: 1
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projects:
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- title: "Agent-Based Simulation of CAR-T Cell Therapy Using BioDynaMo"
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status: Ongoing
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description: |
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Chimeric Antigen Receptor T-cell (CAR-T) therapy has shown great promise
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in treating hematological cancers by harnessing the immune system to target
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and eliminate tumor cells. However, its effectiveness in solid tumors remains
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limited due to challenges such as poor T-cell infiltration, immune suppression,
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and T-cell exhaustion. This project aims to develop a scalable, agent-based
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simulation of CAR-T therapy using BioDynaMo, a high-performance, open-source
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biological simulation platform. The simulation will model key aspects of CAR-T
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dynamics, including T-cell migration, tumor cell engagement, and the influence
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of microenvironmental factors like hypoxia, regulatory T-cells, and
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immunosuppressive cytokines. By simulating various tumor types, including solid
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tumors and leukemias, the model will explore treatment variables such as CAR-T
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dosage, timing of administration, and combination strategies like checkpoint
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inhibitors and cytokine support. The project will deliver a complete and
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well-documented BioDynaMo-based simulation modeling CAR-T cell therapy,
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custom analysis scripts for visualizing tumor regression and evaluating CAR-T
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efficacy, performance benchmarking across therapeutic strategies, and a detailed
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report summarizing insights and future directions. This approach will provide
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valuable insights for optimizing CAR-T therapies, particularly in complex tumor
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microenvironments.
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proposal: /assets/docs/de_la_torre_gonzalez_salvador_proposal_gsoc_2025.pdf
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mentors: Vassil Vassilev, Lukas Breitwieser
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- name: "This could be you!"
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photo: rock.jpg
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info: See <a href="/careers">openings</a> for more info

_pages/team/salvador-delatorre.md

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---
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title: "Compiler Research - Team - Salvador de la Torre Gonzalez"
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layout: gridlay
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excerpt: "Compiler Research: Team members"
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sitemap: false
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permalink: /team/SalvadorDeLaTorreGonzalez
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---
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{% include team-profile.html %}
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