diff --git a/integration/combination/test_function_with_file_system_config.py b/integration/combination/test_function_with_file_system_config.py
index 48d357b5be..50b5b8b209 100644
--- a/integration/combination/test_function_with_file_system_config.py
+++ b/integration/combination/test_function_with_file_system_config.py
@@ -1,6 +1,11 @@
+from unittest.case import skipIf
+
+from integration.config.service_names import EFS
 from integration.helpers.base_test import BaseTest
+from integration.helpers.resource import current_region_does_not_support
 
 
 class TestFunctionWithFileSystemConfig(BaseTest):
+    @skipIf(current_region_does_not_support([EFS]), "EFS is not supported in this testing region")
     def test_function_with_efs_integration(self):
         self.create_and_verify_stack("combination/function_with_file_system_config")
diff --git a/integration/config/service_names.py b/integration/config/service_names.py
index 6862586a70..ec94e1e98c 100644
--- a/integration/config/service_names.py
+++ b/integration/config/service_names.py
@@ -21,3 +21,4 @@
 SQS = "SQS"
 CUSTOM_DOMAIN = "CustomDomain"
 ARM = "ARM"
+EFS = "EFS"