diff --git a/src/lib/autocomplete/autocomplete-trigger.ts b/src/lib/autocomplete/autocomplete-trigger.ts
index 1e328390e6be..31a69af404be 100644
--- a/src/lib/autocomplete/autocomplete-trigger.ts
+++ b/src/lib/autocomplete/autocomplete-trigger.ts
@@ -193,7 +193,7 @@ export class MatAutocompleteTrigger implements ControlValueAccessor, OnDestroy {
   get panelClosingActions(): Observable<MatOptionSelectionChange> {
     return merge(
       this.optionSelections,
-      this.autocomplete._keyManager.tabOut,
+      this.autocomplete._keyManager.tabOut.pipe(filter(() => this._panelOpen)),
       this._escapeEventStream,
       this._outsideClickStream
     );
diff --git a/src/lib/autocomplete/autocomplete.spec.ts b/src/lib/autocomplete/autocomplete.spec.ts
index b9139a06ce99..4743fcd1f229 100644
--- a/src/lib/autocomplete/autocomplete.spec.ts
+++ b/src/lib/autocomplete/autocomplete.spec.ts
@@ -1333,6 +1333,23 @@ describe('MatAutocomplete', () => {
       expect(closingActionSpy).toHaveBeenCalled();
     });
 
+    it('should not emit when tabbing away from a closed panel', () => {
+      const tabEvent = createKeyboardEvent('keydown', TAB);
+
+      input.focus();
+      zone.simulateZoneExit();
+
+      trigger._handleKeydown(tabEvent);
+
+      // Ensure that it emitted once while the panel was open.
+      expect(closingActionSpy).toHaveBeenCalledTimes(1);
+
+      trigger._handleKeydown(tabEvent);
+
+      // Ensure that it didn't emit again when tabbing out again.
+      expect(closingActionSpy).toHaveBeenCalledTimes(1);
+    });
+
     it('should emit panel close event when selecting an option', () => {
       const option = overlayContainerElement.querySelector('mat-option') as HTMLElement;